Tickle Stimulation in Disorders of Consciousness (DoC)
ConditionDisorders of Consciousness
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAnna Estraneo
About this trial
The aim of this project is to investigate whether tickling stimulations can have a short-term effect on the responsiveness of patients with Disorders of Consciousness due to Severe Acquired Brain Injury and to compare this effect with that of neutral tactile stimulations that do not induce tickling.
Eligibility criteria
Qualifiers
Diagnosis of disorders of consciousness (DoC) based on the CRS-R scale;
Age ≥18 years;
Time since the event ≥ 28 days
Disqualifiers
Large craniectomy that may interfere with fNIRS recording; Unstable clinical conditions (e.g., respiratory failure, fever, status epilepticus, etc.);
Fractures, paralysis, injuries, or muscular dystrophy that prevent proper stimulation of the aforementioned body parts;
Lack of informed consent from the legal representative.
Trial design
Treatments tested in this trial
- Tickle stimulation
- Neurophysiological Monitoring with SedLine
Treatment groups
45 Participants
are divided into 1 treatment groupSponsors and collaborators
Anna Estraneo
Lead sponsor
Fondazione Don Carlo Gnocchi Onlus
Sponsor institution
Source ClinicalTrials.gov