Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
About this trial
Despite the good clinical results in terms of outcome with the application of HOPE prior to liver transplantation, very little is still known about the phenotypic and molecular changes that occur during perfusion/preservation during HOPE, particularly with regard to endothelial trophism and activation. Delving into these aspects would be very useful to allow personalised perfusion treatments in the future, thus improving the outcome of transplantation.
Eligibility criteria
Qualifiers
HOPE performed on the liver graft prior to transplantation.
Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis.
Age greater than/equal to 18 years.
Disqualifiers
None
Trial design
Treatments tested in this trial
- histochemical and immunohistochemical analysis
- RT-PCR
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov