TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorGrigore T. Popa University of Medicine and Pharmacy

About this trial

This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer. The investigators will asess the impact of the type of anaesthesia (total intravenous anaesthesia/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass, which will be evaluated using ultrasound, dynamometry and bioimpedance.

Eligibility criteria

Qualifiers

None

Disqualifiers

lack the capacity to consent

extremity amputation

paraplegia

diseases affecting the muscles (such as stroke, lower-limb immobilization from a plaster, neurodegenerative diseases, peripheral neuropathy or muscle dystrophy)

Trial design

Treatments tested in this trial

  • total intravenous anaesthesia
  • sevoflurane anaesthesia

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Grigore T. Popa University of Medicine and Pharmacy

Lead sponsor

Regional Institute of Oncology, Iasi, Romania

Collaborator