To determine the effect of allograft and iPRF with or without collagen membrane on healing of apicomarginal defects : A Randomized Controlled Trial
Patients with no general medical contraindications for oral surgical procedures (ASA-I and ASA-II according to the classification of the American Society of Anesthesiologist's).
Patients aged 18 years and above, presenting with chronic suppurative apical periodontitis in at least one tooth,
Radiographic evidence of apical radiolucency with periodontal pocket depth exceeding 6 mm confined to buccal aspect of the root.
Repeated abscess discharge despite satisfactory root canal treatment. 5.Patients with apicomarginal defects showing a denuded buccal bone plate
Clinical or radiographic evidence of root fracture.
Resorptive processes involving more than apical third of the root.
Chronic generalized periodontitis.
Failed previous endodontic surgery or failed root canal re-treatment.