To study the improvement of constipation symptoms, quality of life and mental state, intestinal function, intestinal hormones, inflammation and immunity, and intestinal flora of constipation subjects after 8-week intervention with Pediococcus acidilactici PA53.
None
Short-term use of items with similar functions to the subject, which affects the judge of the result;
Those who changed their diet type during the study period;
People with severe allergies and immune deficiencies;
Women who are pregnant, breastfeeding or planning to become pregnant;
Parallel
Probiotic
Dietary supplementThe experimental phase of this study had last 8 weeks and each patient will make 3 visits (week 0, week 4, week 8).
Maltodextrin
Dietary supplementThe experimental phase of this study had last 8 weeks and each patient will make 3 visits (week 0, week 4, week 8).
Constipation symptom improvement
Assessing the improvement of constipation in patients using the Bristol Stool Form Scale (BSFS) . In this scale, higher scores indicate softer stool textures, closer to liquid consistency. Scores of 4, 5, and 6 are generally considered ideal stool characteristics.
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