To study the improvement of constipation symptoms, quality of life and mental state, intestinal function, intestinal hormones, inflammation and immunity, and intestinal flora of constipation subjects after 8-week intervention with Pediococcus acidilactici PA53.
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Short-term use of items with similar functions to the subject, which affects the judge of the result;
Those who changed their diet type during the study period;
People with severe allergies and immune deficiencies;
Women who are pregnant, breastfeeding or planning to become pregnant;