To Evaluate Whether IVUS-guided Drug-eluting Stent (DES) Implantation Leads to Better Clinical Outcomes Compared to Conventional Angiography in the Treatment of Chronic Complete Occlusion (CTO) Disease.

ConditionChronic Total Occlusion of Coronary Artery

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorCCRF Inc., Beijing, China

About this trial

This study aims to evaluate the treatment of Chronic total occlusion (CTO) disease. Whether Intravascular Ultrasonography (IVUS) guiding the implantation of drug-eluting stents (DES) will provide better long-term clinical outcomes compared with conventional angiography

Eligibility criteria

Qualifiers

At least 18 years old

Subjects will understand the test requirements, treatment and surgery, and can provide written informed consent

Subjects with clinical symptoms of ischemic heart disease or evidence of myocardial ischemia associated with CTO target vessels and scheduled to undergo Percutaneous coronary intervention (PCI)

Subjects will receive percutaneous coronary intervention

Disqualifiers

Pregnant and lactating women

Severe coronary artery disease, not suitable for PCI

Patients with acute myocardial infarction less than 7 days

Long-term contraindications to DAPT (at least 1 year)

Trial design

Treatments tested in this trial

The guidewire successfully passed the CTO lesion

Treatment groups

1,448 Participants

are divided into 2 treatment groups

Sponsors and collaborators

CCRF Inc., Beijing, China

Lead sponsor

General Hospital of Shenyang Military Region

Sponsor institution

BSC International Medical Trading (Shanghai) Co., Ltd.

Collaborator

Source ClinicalTrials.gov