Tolerance to an Artisanal Bread in a Population Intolerant of the Conventional Bread and Study of Associated Markers

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

About this trial

The objective of this study is to evaluate the effect of consuming an "artisanal" bread for 15 days on gastrointestinal symptoms in individuals intolerant to "conventional" bread.

"Conventional bread" refers to bread made with refined wheat flour (ash = 0.55% of dry matter), containing gluten, and leavened with baker's yeast (Saccharomyces cerevisiae). "Artisanal bread" refers to bread made with whole wheat flour (ash = 1.50% of dry matter) from an ancient durum wheat variety (Russello) and leavened with sourdough.

Eligibility criteria

Qualifiers

Normal weight (18 < BMI < 25 kg.m-2)

Male or female

18 to 65 years old

Adults reporting intolerance to "conventional" bread

Disqualifiers

People under protective supervision: legal guardianship, tutorship or curatorship

People with eating disorders (anorexia, bulimia, binge eating)

Any known food allergy

Women who are pregnant or potentially pregnant (based on a positive urine pregnancy test at inclusion)

Trial design

Treatments tested in this trial

  • Artisanal Bread

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Lead sponsor

UMR 914 PNCA - AgroParisTech, INRA, Université Paris-Saclay

Collaborator