Tonic Pain and Transauricular Vagal Nerve Stimulation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16-60
SponsorAalborg University
About this trial
This study aims to explore the effect of burst-taVNS (electric stimulation of the concha cymba) on tonic (capsaicin-induced skin pain) and acute (pressure pain sensitivity) experimental pain and cardioception. Primary outcomes include pain intensity. Secondary outcomes include sensory thresholds, resting heart rate (EKG), pupillary measurements and conditioned pain modulation.
Eligibility criteria
Qualifiers
Healthy
Speak and understand English
18-60 years old.
Disqualifiers
Pregnant and/or breastfeeding
Regular use of cannabis, opioids or other drugs
Current or previous neurologic, musculoskeletal, mental, or other illnesses (e.g., brain or spinal cord injuries, degenerative neurological disorders, major depression, cardiovascular disease, chronic lung disease, etc.)
Current regular (once or more a week) use of analgesic medication or other medication which may affect the trial (including paracetamol and NSAIDs)
Trial design
Treatments tested in this trial
- taVNS
- Earlobe Stimulation
- Sham (No Treatment)
Treatment groups
36 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov