Topo-Pachymetric Customized Accelerated Epi-On Vs Accelerated Epi-Off Corneal Cross Linking in Keratoconus Management

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKasr El Aini Hospital

About this trial

The objective of this study is to compare the clinical effectiveness and safety of Topo-Pachymetric Customized Accelerated Epithelium-On (aCFXL) to Standard Accelerated Epithelium-Off (aCXL) Corneal Collagen Cross-Linking in the management of keratoconus. The study aims to evaluate visual and structural outcomes, to provide valuable insights into optimizing treatment strategies.

Eligibility criteria

Qualifiers

Age: 18 years or older

Corrected distance visual acuity (CDVA) of ≥ 0.3 Snellen.

Central corneal thickness (de-epithelialized) of ≥ 400 micron.

Corneal endothelial count of ≥ 2000.

Disqualifiers

Previous eye surgery

The presence of lesions other than keratoconus, central or paracentral scaring

History of Cross linking

History of viral keratitis

Trial design

Treatments tested in this trial

  • Corneal cross linking

Treatment groups

55 Participants
are divided into 3 treatment groups

Sponsors and collaborators