Total Intravenous Anesthesia in Patients Undergoing Craniotomy
ConditionAnesthesia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-60
SponsorZagazig University
About this trial
Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.
Eligibility criteria
Qualifiers
Patient acceptance.
Physical status: American Society of Anesthesiologists Physical Status (ASA) 1& II.
Body mass index ≤ 30 kg/m2.
Type of operation: elective craniotomy for brain tumor resection.
Disqualifiers
Patient with hemodynamic instability or anticipated postoperative mechanical ventilation.
Patients with a known history of allergy to the study drugs.
Advanced hepatic, renal, cardiovascular, and neurologic diseases.
Patients with chronic opioid use.
Trial design
Treatments tested in this trial
- Dexmedetomidine
- Fentanyl
- Magnesium
Treatment groups
108 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov