Towards a Targeted Ultrasound Neuromodulation Intervention for Alcohol Abuse Disorders

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-60
SponsorUniversity of Plymouth

About this trial

This study explores the potential of transcranial ultrasound stimulation (TUS) as an innovative therapeutic approach for individuals with Alcohol Use Disorder. By targeting specific brain regions associated with compulsive behaviors and reward dysfunction, the researchers aim to assess the safety and efficacy of TUS in reducing symptoms and enhancing cognitive flexibility.

Eligibility criteria

Qualifiers

Male or female, aged 21-55 years, and fluent English speaking.

Participants score ≥ 20 on the AUDIT.

Participant is willing and able to give informed consent for participation in the trial.

Participant is willing to comply with all trial requirements and committed to participating in all six testing sessions.

Disqualifiers

serious head trauma or brain surgery

(first-degree relatives with) epilepsy, convulsion, or seizure

diagnosis of a neurological or psychiatric disorder (other than AUD)

adverse reactions to non-invasive brain stimulation

Trial design

Treatments tested in this trial

  • low intensity transcranial focused ultrasound stimulation (TUS)

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators