Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Infant

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-26
SponsorChildren's Hospital Medical Center, Cincinnati

About this trial

Individuals with Fragile X Syndrome show differences in how they understand and learn language from infancy. They frequently have lifelong delays in speech and language as well. In addition, they experience other auditory symptoms, including being very sensitive to certain sounds as well as being more sensitive than others to loud sounds. The underlying brain activity for sound perception and speech learning in Fragile X is not well understood, especially in the infant and toddler years. This study uses behavioral assessment of speech and language abilities, neuroimaging, and hearing tests to understand how speech and hearing are different in children with Fragile X Syndrome.

Eligibility criteria

Qualifiers

Diagnoses of Fragile X Syndrome, Typical Development, or History of Premature Birth

able to sit independently

English is spoken at home

Disqualifiers

For all participants: no seizures in the past 6 months

For typical development group and Fragile X group: not born prior to 32 weeks gestation

Trial design

Treatments tested in this trial

  • Speech discrimination

Treatment groups

30 Participants
are divided into 1 treatment group