Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse Injured Tendons

ConditionTendinopathy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorUniversity Hospital Bispebjerg and Frederiksberg

About this trial

The goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon overuse injury (tendinopathy). The main questions it aims to answer are:

* Is the method sensitive enough to detect the smallest blood vessels * What information about the blood flow can be obtained (flow velocity, pressure, shape of the vessels) * Can the flow in an injured tendon be distinguished from that of a healthy one

Participants will receive a non-invasive ultrasound examination of their Achilles (heel) or patellar (knee) tendon, using an advanced high frequency research ultrasound system.

Researchers will compare participants with either an Achilles or patellar tendon overuse injury to participants with healthy tendons, to see if there are distinct differences in the blood vessels that could help diagnose and treat the injuries.

Eligibility criteria

Qualifiers

18 to 70 years of age.

BMI below 30.

Able to lie still for 1 minute.

Capable of providing signed informed consent.

Disqualifiers

Pregnancy.

Dementia.

Smoking.

Diabetes.

Trial design

Treatments tested in this trial

  • Super-Resolution Ultrasound Imaging of Erythrocytes (SURE)

Treatment groups

135 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University Hospital Bispebjerg and Frederiksberg

Lead sponsor

Technical University of Denmark

Collaborator