TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity College, London

About this trial

TRACERx EVO is a programme of work using a prospective observational cohort study of participants with early- and late-stage non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC) and pleural mesothelioma.

Eligibility criteria

Qualifiers

Written Informed consent

Agreement to be followed up (including on-study assessments and sample collection) every 3 months in the first 2 years and then 6 monthly.

Agreement to be followed up at a TRACERx EVO site

Participants ≥18 years of age, with early stage I-IIIB NSCLC disease who are eligible for primary surgery

Disqualifiers

Other active malignancy

Any other* malignancy diagnosed or relapsed at any time, which is currently being treated (including by hormonal therapy).

Any other* current malignancy or malignancy diagnosed or relapsed within the past 3 years**.

*Exceptions are: non-melanomatous skin cancer, stage 0 melanoma in situ, and in situ cervical cancer

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

600 Participants
are grouped into 3 trial groups

Sponsors and collaborators

University College, London

Lead sponsor

Cancer Research UK

Collaborator