About this trial
Laparoscopic surgery has become increasingly common in pediatric patients due to its minimally invasive nature and favorable postoperative outcomes. However, the creation of pneumoperitoneum with carbon dioxide (CO₂) insufflation and the use of the Trendelenburg position may increase intra-abdominal pressure and potentially influence intracranial pressure and cerebral hemodynamics. These physiological changes may affect cerebral perfusion and oxygenation during surgery.
This prospective observational study aims to evaluate cerebral hemodynamic changes during pediatric laparoscopic inguinal hernia repair using transcranial Doppler ultrasonography (TCD) and near-infrared spectroscopy (NIRS). Middle cerebral artery (MCA) flow velocities and pulsatility index (PI) will be measured with TCD as indirect indicators of intracranial pressure, and their relationship with cerebral oxygen saturation measured by NIRS will be assessed. In addition, mean arterial pressure and end-tidal CO₂ values will be recorded to evaluate their association with cerebral hemodynamic changes during different phases of surgery.
Eligibility criteria
Qualifiers
Scheduled for elective laparoscopic inguinal hernia repair
American Society of Anesthesiologists (ASA) physical status I-II
Undergoing surgery under general anesthesia
Written informed consent obtained from parent or legal guardian
Disqualifiers
Intracranial pathology that may increase intracranial pressure
History of cerebrovascular disease
Development of intraoperative hemodynamic instability
Severe cardiac or respiratory disease
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Hanife Kabukcu
Lead sponsor
Akdeniz University
Sponsor institution