About this trial
The purpose of this study is to determine if the enhancement of electroencephalographic (EEG) slow-wave activity using transcranial electrical stimulation (TES) at Slow Oscillation (SO) frequency, during a restricted period of nocturnal sleep, enhances the restorative properties of that period of sleep and improves performance during a subsequent period of sleep deprivation.
Eligibility criteria
Qualifiers
Healthy men and non-pregnant, non-lactating women 18 to 39 years of age (inclusive)
Must demonstrate adequate comprehension of the protocol, by achieving a score of at least 80% correct on a short multiple-choice quiz. Individuals who fail to achieve a passing score on the initial quiz will be given one opportunity to retest after a review of protocol information. Individuals who fail the comprehension assessment for the second time will be disqualified.
Disqualifiers
Self-reported habitual nightly sleep amounts outside the target range of 6 - 9 hours (i.e., less than 6 hours per night or more than 9 hours per night, on average) (Post-consent Checklist)
Self-reported nighttime lights-out times earlier than 2100 hours on average during weeknights (Sunday through Thursday) or later than 2300. (Post-consent Checklist)
Self-reported morning wake-up times later than 0800 on average during weekdays (Monday through Friday) (Post-consent Checklist)
Self-reported habitual napping (> 1 time a week in conjunction with normal sleep habits) (Post-consent Checklist)
Trial design
Treatments tested in this trial
- NeuroConn DC Stimulator PLUS
- SHAM TES
Treatment groups
Sponsors and collaborators
U.S. Army Medical Research and Development Command
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Collaborator