Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-39
SponsorU.S. Army Medical Research and Development Command

About this trial

The purpose of this study is to determine if the enhancement of electroencephalographic (EEG) slow-wave activity using transcranial electrical stimulation (TES) at Slow Oscillation (SO) frequency, during a restricted period of nocturnal sleep, enhances the restorative properties of that period of sleep and improves performance during a subsequent period of sleep deprivation.

Eligibility criteria

Qualifiers

Healthy men and non-pregnant, non-lactating women 18 to 39 years of age (inclusive)

Must demonstrate adequate comprehension of the protocol, by achieving a score of at least 80% correct on a short multiple-choice quiz. Individuals who fail to achieve a passing score on the initial quiz will be given one opportunity to retest after a review of protocol information. Individuals who fail the comprehension assessment for the second time will be disqualified.

Disqualifiers

Self-reported habitual nightly sleep amounts outside the target range of 6 - 9 hours (i.e., less than 6 hours per night or more than 9 hours per night, on average) (Post-consent Checklist)

Self-reported nighttime lights-out times earlier than 2100 hours on average during weeknights (Sunday through Thursday) or later than 2300. (Post-consent Checklist)

Self-reported morning wake-up times later than 0800 on average during weekdays (Monday through Friday) (Post-consent Checklist)

Self-reported habitual napping (> 1 time a week in conjunction with normal sleep habits) (Post-consent Checklist)

Trial design

Treatments tested in this trial

  • NeuroConn DC Stimulator PLUS
  • SHAM TES

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

U.S. Army Medical Research and Development Command

Lead sponsor

Walter Reed Army Institute of Research (WRAIR)

Collaborator