Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorVA Office of Research and Development

About this trial

This study effects the effects of transcutaneous cervical vagal nerve stimulation (tcVNS) or a sham control on brain, physiology, and PTSD symptoms in Veterans with posttraumatic stress disorder (PTSD). Veterans undergo brain imaging and physiological measures in conjunction with traumatic scripts before and after three months of twice daily treatment with tcVNS or sham stimulation at home.

Eligibility criteria

Qualifiers

Veterans between the ages of 18 and 75 will be included with a diagnosis of PTSD based on DSM-5 criteria

Disqualifiers

a history of mild traumatic brain injury (mTBI) based on VA Criteria

moderate or greater TBI

positive pregnancy test

meningitis or other neurological disorder

Trial design

Treatments tested in this trial

  • tcVNS
  • Sham

Treatment groups

80 Participants
are divided into 2 treatment groups