Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUnity Health Toronto
About this trial
TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.
Eligibility criteria
Qualifiers
≥18 and ≤65 years of age
Planned cardiac surgery using cardiopulmonary bypass
Informed consent obtained
Preoperative European System for Cardiac Operative Risk Evaluation (EuroSCORE I) of 6 or more
Disqualifiers
Patients who refuse participation
Patients who are unable to receive or who refuse blood products
Patients who are involved in a preoperative autologous pre-donation program
Patients who are having a heart transplant or having surgery solely for an insertion of a ventricular assist device
Trial design
Treatments tested in this trial
- Restrictive Transfusion Strategy
- Liberal transfusion strategy
Treatment groups
1,440 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov