TRansmural hEaliNg Definition in CroHn's Disease (TRENCH 1)

ConditionCrohn Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorGroupe d'Etude Therapeutique des Affections Inflammatoires Digestives

About this trial

Multicenter prospective cross-sectional study of CD patients, its aim is the construction of an objective and reproducible system for evaluation of Transmural healing in Crohn's Disease (CD).

Primary objective : Objective definition of depth or grade of transmural healing in relation to radiologic signs observed during Magnetic Resonance Enterography (MRE) in CD

Eligibility criteria

Qualifiers

≥ 18 years of age

Patient diagnosed with CD for more than 6 months with histological confirmation available in his medical record.

Indication for MRE based on routine clinical practice validated by the treating physician

Any CD treatment will be authorized, such as biologicals (infliximab, adalimumab, vedolizumab, ustekinumab…), or immunomodulators (azathioprine, 6-mercaptopurine, methotrexate…).

Disqualifiers

Pregnancy during the study

People unable to give consent (because of their physical or mental state)

Absence of written consent

Ulcerative colitis or unclassified IBD

Trial design

Treatments tested in this trial

  • Magnetic Resonance Enterography (MRE)

Treatment groups

No treatment groups listed