This study is designed to investigate a novel approach to offer more ESRD participants the benefits associated with renal transplantation by increasing the supply of available allografts
Adults > 50 years
Willing and able to understand and sign informed consent
Must have high-quality pre-operative cross-sectional imaging (CT or MRI) to determine tumor characteristics and perform parenchymal volume analysis for split renal function
Patient who is a candidate for partial nephrectomy for cT1a mass who understands that partial nephrectomy is standard of care for such mass but wishes to be an altruistic kidney donor (primary incentive is altruism) via radical nephrectomy with loss of the entire kidney.
Known familial RCC syndrome
Preoperative GFR < 80 ml/min/1.73 m2
Proteinuria on urine dipstick or urinalysis (≥1+ considered positive)
Predicted new baseline GFR (NBGFR) following radical nephrectomy would be < 45