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Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery

ConditionsTransversus Thoracic Plane BlockCardiac SurgeryPost Operative Pain
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSaint-Joseph University

About this trial

The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are:

1. does Transversus Thoracic Plane Block decrease perioperative pain after cardiac surgery more than the standard analgesic treatment? 2. Are the results different if the investigators perform Transversus Thoracic Plane Block before surgery or at the end of surgery?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Previous cardiac surgery

Urgent surgery

Pregnant women

Allergy to local anesthetics

Trial design

Design model

Parallel

Treatments tested in this trial

  • Transversus Thoracic Plane Block

    Procedure/Surgery

    The Transversus Thoracic Plane Block is a recent regional anesthesia technique. It provides analgesia for the anterior cutaneous branches of the intercostal nerves T2-6 to the medial anterior chest wall via a single injection of local anesthesia between the internal intercostal muscle and the transversus thoracic muscle located between the third and fourth (or fourth and fifth) intercostal space. It is noteworthy that the TTPB can consequently reduce pulmonary morbidity and the need for high-dose opioids.

Treatment groups

150 Participants
are divided into 3 treatment groups
Group A: PlaceboNo intervention 0 interventions
Group B: Transversus Thoracic Plane Block preActive comparator 1 intervention
Group C: Transversus Thoracic Plane Block postActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

postoperative pain score

The primary outcome is Postoperative Pain Score: Numeric rating scale (NRS) ratings will be assessed at T1 (= upon patient awakening), T2 (= 12 hours postoperatively), T3 (= 24 hours postoperatively) as well as during various painful moments (coughing, drain removal, mobilization). Numeric rating scale (NRS) is a unidimensional measure of pain intensity. It consists of the patient evaluating his pain out of a series of numbers ranging from 0 to 10, where the 2 respective endpoints are "0 = no pain" and "10 = worst possible pain."

Time frame
First 24h postoperatively

Secondary outcomes

1

Perioperative opioid requirement

Total dose of opioids required during surgery and 24h postoperatively

Time frame
First 24h postoperatively
2

Time to first opioid administration

Time to first opioid administration after surgery

Time frame
First 24h postoperatively
3

Time to extubation

Time between arrival to cardiac intensive care unit and extubation

Time frame
First 24h postoperatively
4

Patient satisfaction at 24 hours post surgery

Patient satisfaction is measured by asking patients one question at 24 hours post surgery: "On a scale from 0 to 10, 0 = not satisfied at all, 10 = extremely satisfied, how satisfied do you feel concerning pain management during the first 24 hours after surgery? "

Time frame
First 24h postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Saint-Joseph University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: