About this trial
Traumatic Brain Injury (TBI) often results in a wide array of cognitive impairments, which can significantly diminish quality of life for affected individuals. While traditional rehabilitation methods typically adopt a standardized approach, it's crucial to acknowledge the significant heterogeneity within the TBI patient population. Neglecting these variations reduces the likelihood of otherwise effective treatments being considered for widespread adoption. Emerging evidence highlights the potential of transcranial direct current stimulation (tDCS) as a promising adjunctive therapy. tDCS, a noninvasive and safe neuro-rehabilitative procedure, has shown efficacy when integrated with cognitive training across various neurological disorders, such as depression, post-stroke aphasia, and neurodegenerative conditions.
This study aims to investigate the effectiveness of tDCS paired with behavioral therapy, particularly cognitive training, in improving cognition and executive function in chronic TBI patients. Additionally, tDCs targets in the current study will be tailored to each individual patient, recognizing the patient's unique needs and circumstances
Eligibility criteria
Qualifiers
Diagnosis of traumatic brain injury (TBI) at least 2 years prior to participation
Right-handed
English - speaking
Disqualifiers
Uncorrected visual impairment
Uncorrected hearing impairment
Stroke or other premorbid neurological disorders affecting the brain
Premorbid learning disorders
Trial design
Treatments tested in this trial
- Active tDCS on the DLPFC + Cognitive Intervention(s)
- Sham tDCS on the DLPFC + Cognitive Intervention(s)
Treatment groups
Locations
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
Ybrain Inc.
Collaborator