Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-90
SponsorThe University of Texas at Dallas

About this trial

The purpose of this research study is to examine the effects of transcranial Direct Current Stimulation (tDCS) on verbal retrieval and cognition and sensorimotor control and to determine if tDCS can be used as a way to improve retrieval, sensory, and motor abilities in individuals with Parkinson's disease (PD).

Eligibility criteria

Qualifiers

Diagnosed with PD having a verbal fluency deficit based on neuropsychological test (T-score < 40 or a T-score <-1.0 SD below the average T-score): Semantic Object Retrieval Test (SORT), COWAT (both letter and category fluency), Boston Naming Test (BNT), Rey Auditory Verbal Learning Test (RAVLT)

50 - 90 years old

Capable of understanding and signing an informed consent (able to answer consent comprehension questions)

Fluent in speaking and reading English

Disqualifiers

Montreal Cognitve Assessment (MOCA) score <23, unless an accompanying study partner/caregiver is with them and we can obtain the written consent of both the participant and the participant's accompanying study partner/caregiver (i.e., the participant's spouse, adult child, parent, or adult sibling);

history of seizures;

unexplained episodes of loss of consciousness (as these may be related to brain alterations or epilepsy);

suffering from severe or frequent headaches;

Trial design

Treatments tested in this trial

  • transcranial direct current stimulation
  • Sham transcranial direct current stimulation

Treatment groups

20 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The University of Texas at Dallas

Lead sponsor

University of Texas Southwestern Medical Center

Collaborator