Treatment of Negative Symptoms of Schizophrenia by rTMS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre hospitalier de Ville-Evrard, France
About this trial
The purpose of this study is to assess the effectiveness of rTMS on the negative symptoms of schizophrenia in real conditions. It will also provide a regulatory framework to rTMS treatments under these conditions. 4 types of rTMS protocols are proposed, allowing to adapt to patients and their tolerances.Treatment lasts between 2 and 4 weeks, with a follow-up period of 3 months after treatment to observe relapses.To assess the evolution of negative symptoms between baseline and the end of treatment, investigators use SANS (Scale for the Assessment of Negative Symptoms).
Eligibility criteria
Qualifiers
Patient over 18 years of age
Patient diagnosed with schizophrenia according to the DSM-V criteria (Diagnostic and Statistical Manual of Mental Disorder V5, 2013)
Stable drug treatment for at least 4 weeks
Patient (or legal representative) willing to participate in the study and having signed an informed consent
Disqualifiers
Present a contraindication to TMS: intracranial foreign body, unstabilized epilepsy, cochlear implant, pace-maker
Presence of an unstabilized medical condition
Pregnant woman
Woman of childbearing potential and without effective contraception
Trial design
Treatments tested in this trial
- repetitive Transcranial Magnetic Stimulation
Treatment groups
124 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov