Treatment of Post-Stroke Central Pain
ConditionCentral Post-Stroke Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNanchong Central Hospital
About this trial
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.
Eligibility criteria
Qualifiers
Diagnosis of central post-stroke pain (CPSP) according to the International Association for the Study of Pain (IASP) criteria
Clear history of stroke confirmed by cranial CT or MRI
Pain occurring after stroke and distributed in body parts corresponding to central nervous system injury
Pain with neuropathic characteristics (e.g., burning sensation, electric shock sensation, needle prick sensation)
Disqualifiers
History of chronic pain before stroke
Severe cognitive impairment that prevents cooperation with pain assessment (Mini-Mental State Examination, MMSE < 15 points)
Contraindications to spinal cord stimulation (SCS), such as coagulation disorders, active infections, or mental diseases that prevent cooperation
Malignant tumors or other severe organic diseases with expected survival < 1 year
Trial design
Treatments tested in this trial
- stSCS+Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline)
- Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline)
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov