Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorSpaulding Rehabilitation Hospital
About this trial
This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.
Eligibility criteria
Qualifiers
Previous ACL reconstruction using an autograft or allograft in the knee with PTOA
Minimum of one year following ACL reconstruction surgery
Between ages of 18 and 55
No clear contraindication to complete protocol including mechanical symptoms which would limit ability to complete the study
Disqualifiers
Have previously received injections to the knee joint within the past 3 months
Women who are pregnant or those who are planning to become pregnant. This is due to the fact that pregnancy will reduce participants activity after the treatment and the safety concerns related to shockwave treatment. - Participants with neuropathy affecting sensation to pain
Participants with a known underlying cardiac disease that could be affected by shockwave therapy
Chronic rheumatological conditions, immunodeficiency, severe asthma, connective tissue disorder (i.e. Ehlers-Danlos Syndrome), or other medical conditions (ex. active malignancy, severe asthma) outside of PTOA that are known to impact inflammatory state or requiring chronic use of oral or intravenous immune modulatory medications. Asthma requiring use of inhalers only is not an exclusion criteria
Trial design
Treatments tested in this trial
- extracorporeal shockwave therapy (ESWT)
- Sham Comparator
Treatment groups
70 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov