Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorVanderbilt University Medical Center

About this trial

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.

Eligibility criteria

Qualifiers

Patients with autonomic failure and with supine hypertension from all races

Disqualifiers

All medical students

Pregnant women

High-risk patients (e.g. heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction)

History of serious allergies or asthma.

Trial design

Treatments tested in this trial

  • continuous positive airway pressure (CPAP)
  • Placebo

Treatment groups

12 Participants
are divided into 2 treatment groups