Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Cincinnati
About this trial
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Eligibility criteria
Qualifiers
Adult patients (≥18 years)
Moderate-to-severe pre-stroke functional disability, defined as mRS 3-4, for at least 3 months prior to stroke onset
Presenting to study hospital within 24 hours of last known well time
Diagnosis of acute ischemic stroke
Disqualifiers
Known diagnosis of a terminal cancer or terminal illness at the time of stroke
Assessment of pre-stroke functional status cannot be performed during the hospital stay
Pre-stroke disability deemed temporary in the investigator's opinion (for example, recovering from a general medical illness or traumatic bodily injury)
Trial design
Treatments tested in this trial
- Endovascular Stroke Treatment
- Medical Management
Treatment groups
1,060 Participants
are divided into 1 treatment groupSponsors and collaborators
University of Cincinnati
Lead sponsor
Patient-Centered Outcomes Research Institute
Collaborator
University of California, Los Angeles
Collaborator
Icahn School of Medicine at Mount Sinai
Collaborator
Source ClinicalTrials.gov