Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-55
SponsorWeill Medical College of Cornell University

About this trial

The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention and be cost-effective, especially among underserved populations.

Eligibility criteria

Qualifiers

Age 18 years - 55 years

Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site.

Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider

Patients with prior OCS but planned to repeat OCS are eligible

Disqualifiers

Patients who have previously completed a multigene hereditary cancer syndrome panel

Patients who have a hematologic cancer or hematologic pre-cancer

Patients who have a history of an autologous bone marrow transplant

Trial design

Treatments tested in this trial

  • MyRisk Hereditary Cancer Test

Treatment groups

550 Participants
are divided into 2 treatment groups

Sponsors and collaborators