Trial of Partial Enteral Nutrition With Dairy Free Diet in Eosinophilic Esophagitis
ConditionEosinophilic Esophagitis (EoE)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-21
SponsorKate Farms Inc
About this trial
This study aims to introduce a new dietary therapy for Eosinophilic Esophagitis (EoE) patients by using partial enteral nutrition (PEN) to enhance remission rates and explore how this approach affects immune function, gut microbiota, and environmental toxin exposures.
Eligibility criteria
Qualifiers
Pediatric patients 1 year to 21 of age presenting with chronic symptoms of dysphagia, odynophagia, vomiting or heartburn, chronic abdominal pain, weight loss, picky eating, to outpatient gastroenterology clinic and are planning to undergo EGD for evaluation.
Disqualifiers
Non-English-Speaking Subjects, adults unable to consent, wards of the state, pregnant women, and prisoners will be excluded from the study.
Patients with autoimmune conditions such as inflammatory bowel disease. Patients with prior esophageal or intestinal surgeries.
Patients with history of eating disorders or ARFID.
Patients with fistulizing or fibrotic disease on baseline EGD.
Trial design
Treatments tested in this trial
- Partial enteral nutrition (PEN) with dairy elimination
- Dairy elimination alone
Treatment groups
36 Participants
are divided into 3 treatment groupsSponsors and collaborators
Kate Farms Inc
Lead sponsor
Seattle Children's Hospital
Collaborator
Source ClinicalTrials.gov