About this trial
This study aims to evaluate the impact of the triglyceride-glucose (TyG) index on the angiographic profiling of non-diabetic patients with premature coronary artery disease (CAD).
Eligibility criteria
Qualifiers
Age ≥18 years old.
Both sexes.
Non-diabetic patients [no history of diabetes, hemoglobin A1C (HbA1C) < 6.5%, fasting glucose < 126 mg/dL].
Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography.
Disqualifiers
Known diabetes mellitus (type 1 or type 2).
Previous history of coronary revascularization.
Severe hepatic or renal dysfunction [alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)< 30 mL/min/1.73 m²].
Malignant disease, autoimmune disease, or systemic inflammatory disorders.
Trial design
Treatments tested in this trial
- Coronary Angiographic Assessment