Trunk Inclination, Positive End-expiratory Pressure, and Lung Recruitability
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorZhongda Hospital
About this trial
This multicenter, physiological, observational study hypothesizes that in moderate to severe ARDS, trunk inclination unloads the chest wall, but its impact on lung mechanics depends on PEEP levels and lung recruitability.
Eligibility criteria
Qualifiers
Intubated moderate and severe ARDS according to the Berlin definition (PaO2/FiO2 ratio <= 200 mmHg)
Under continuous sedation with or without paralysis
Disqualifiers
Age <18 years
Bronchopleural fistula
Pure COPD exacerbation
Contraindication to EIT monitoring (e.g. burns, pacemaker, thoracic wounds limiting electrode belt placement)
Trial design
Treatments tested in this trial
- Specific lung recruitment maneuvers and decremental PEEP steps
Treatment groups
40 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov