Tubeless VATS for Mediastinal Neoplasm
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorShuben Li
About this trial
In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.
Eligibility criteria
Qualifiers
Mediastinal neoplasm was diagnosed by chest enhanced CT
The patients with age ≥ 18 and ≤ 80 years old
The patients whose tumor diameter was <6 cm
ASA grade: I-III
Disqualifiers
Imaging examinations revealed that the tumor had invaded adjacent organs, with evidence of pleural or pericardial dissemination, as well as lymphatic and/or hematogenous metastases
Patients with a confirmed history of congestive heart failure, poorly controlled angina despite medical therapy, electrocardiogram-confirmed myocardial infarction with transmural involvement, uncontrolled hypertension, clinically significant valvular heart disease, or high-risk arrhythmias not adequately managed
Patients with concurrent active malignancies
Trial design
Treatments tested in this trial
- Non-intubated VATS for mediastinal neoplasm
- Intubated VATS for mediastinal neoplasm
Treatment groups
132 Participants
are divided into 2 treatment groupsSponsors and collaborators
Shuben Li
Lead sponsor
The First Affiliated Hospital of Guangzhou Medical University
Sponsor institution
The First Affiliated Hospital of Guangzhou Medical University
Collaborator
Source ClinicalTrials.gov