Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital
About this trial
This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioids) in patients undergoing major orthopaedic surgery. The main objective is to inform the design and feasibility of the definitive RCT.
Eligibility criteria
Qualifiers
Patients 18 years of age or older
Underwent a major operative orthopaedic procedure
Disqualifiers
Contraindication for NSAIDs.
Preoperative chronic opioid use (preoperative use of >14 days and average of >30 Morphine Milligram Equivalents per day).
Active treatment for opioid use disorder.
Previous or current illicit drug use.
Trial design
Treatments tested in this trial
- Discharge pain medication prescription
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Massachusetts General Hospital
Lead sponsor
McMaster University
Collaborator
Source ClinicalTrials.gov