About this trial
The main objective of the project is to demonstrate that in patients with heart failure and QRS complex of nonRBBB morphology lasting over 130 ms, UHF-ECG can differentiate patients with trueLBBB from IVCD better than existing approaches based on the assessment of QRS complex morphology and duration from 12-lead ECG.
Another goal of the proposed study is to demonstrate that trueLBBB patients will benefit more from CRT using left bundle branch pacing than from CRT using biventricular pacing.
The final aim of the project is to demonstrate that the echocardiographic and clinical response in patients with intraventricular conduction disturbance will be dependent on the degree of reduction in ventricular dyssynchrony after CRT.
Eligibility criteria
Qualifiers
HF due to ischemic or non-ischemic cardiomyopathy
known coronary angiography
NYHA II-IV
LVEF ≤40%
Disqualifiers
Age ˂18 years
heart failure from reversible causes
Moderate to severe aortic stenosis
pregnancy
Trial design
Treatments tested in this trial
- LBBAP CRT device implantation
- BVP-CRT