Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age4-18
SponsorKocaeli University

About this trial

This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities. It is designed as a prospective, cross-sectional, observational study. Planned ultrasound-based assessments include parameters such as muscle thickness, pennation angle, fascicle length, echo intensity, tissue stiffness (via shear wave elastography), and microvascular flow (via superb microvascular imaging). These measurements are intended to be compared with standard clinical evaluations, including the GMFCS, GMFM-66, MAS, MACS, and Tardieu Scale. The study seeks to contribute to a better understanding of the relationship between muscle architecture and functional outcomes, with the goal of generating insights that may inform individualized rehabilitation planning.

Eligibility criteria

Qualifiers

Diagnosis of spastic cerebral palsy (SCP) according to the criteria defined by Rosenbaum et al. (2007)

Age between 4 and 18 years

Gross Motor Function Classification System (GMFCS) Level I, II, or III

Manual Ability Classification System (MACS) Level I, II, III, or IV

Disqualifiers

Non-spastic types of cerebral palsy (e.g., dyskinetic, ataxic)

Diagnosis of neuromuscular disorders other than cerebral palsy (e.g., hereditary neuropathy, myopathy)

Presence of muscle contractures or fixed deformities in the limbs selected for ultrasound and clinical assessment

Cognitive or behavioral impairments that prevent cooperation during ultrasound or clinical evaluation

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

36 Participants
are grouped into 1 trial group

Sponsors and collaborators