Ultrasonographic Evaluation of Talar Cartilage Thickness in Patients With Spinal Cord Injury
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorGaziosmanpasa Research and Education Hospital
About this trial
Spinal cord injury patients often present with musculoskeletal comorbidities, including osteoarthritis. Early detection of cartilage damage is important for preventing osteoarthritis progression. This study aims to compare the talar cartilage thicknesses of spinal cord injury patients with healthy subjects. The secondary aim is to investigate a correlation between the talar cartilage thickness and disease-related parameters. The patient group is to be assessed for talar cartilage thickness (via ultrasound), functional status, spasticity, and ambulation levels.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged between 18 to 60 years,
Cervical, thoracal or lumber level of spinal cord injury
AIS (American Spinal Injury Association Impairment Scale) Level A, B, C, or D
Assisted ambulation of any kind
Disqualifiers
Patients with sacral level injury
AIS E
MAS 4 level of spasticity
History of any lower extremity operation
Trial population
Thirty-eight SCI patients who apply to Physical Medicine and Rehabilitation outpatient and inpatient clinic between November 2025-January 2026 will be included in the study. Thirty-eight age, gender, and BMI-matched healthy participants who are literate, give oral and written consent without any additional disease will be formed as the control group.
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
76 Participants
are grouped into 2 trial groupsGroup A: Patient group
Group B: Control group
Trial outcomes
Primary outcomes
1
Talar cartilage thickness
The talar cartilage of both lower extremities are to be assessed with ultrasound
Time frame
BaselineSecondary outcomes
1
Functional Independence Measure (FIM) score
Functional Independence Measure scores will be held for the patient group in order to assess functional independence. This 18-item scale ranges between 18-126, higher scores indicating better outcomes.
Time frame
Baseline2
Modified Ashworth Scale (MAS)
The spasticity level of patients are to be recorded for both ankle flexor and extensors via Modified Ashworth Scale. This scale ranges from 0 to 4; 0 indicating no spasticity, and 4 indicating severe increase in muscle tone with rigid joint.
Time frame
Baseline3
Walking Index for Spinal Cord Injury II (WISCI II)
Ambulatory status of the patients will be recorded with this measuring scale, ranging between 0 (non ambulatory) to 20 (able to walk 10 meters with no devices/orthosis/assistance).
Time frame
BaselineSponsors and contacts
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Source ClinicalTrials.gov