Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16+
SponsorAssiut University

About this trial

The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults. and the role of nerve conduction study and neuromuscular ultrasound

The main questions it aims to answer are:

Does placental growth factor improve outcome after peripheral nerve injury? Does platelet rich plasma improve outcome after peripheral nerve injury? Researchers will compare drug both drugs to each other and will follow up the results via NCS and NMUS

Participants will be classified into 3 random groups:

one group will receive perineural injection of placental growth factor, the other group will receive peri neural PRP injection, third group will only be followed up without intervention Follow up of each patients will be done at 3 and 6 months

Eligibility criteria

Qualifiers

Adult patients older than 16 yrs old.

Patients with traumatic median or ulnar nerve injury who are complaining of symptoms or functional disability.

Patients with these injuries for more than 3 months

Disqualifiers

1- Presence of other causes of nerve affection (entrapment, Diabetes, etc).

Trial design

Treatments tested in this trial

  • perineural injection

Treatment groups

75 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators