About this trial
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults. and the role of nerve conduction study and neuromuscular ultrasound
The main questions it aims to answer are:
Does placental growth factor improve outcome after peripheral nerve injury? Does platelet rich plasma improve outcome after peripheral nerve injury? Researchers will compare drug both drugs to each other and will follow up the results via NCS and NMUS
Participants will be classified into 3 random groups:
one group will receive perineural injection of placental growth factor, the other group will receive peri neural PRP injection, third group will only be followed up without intervention Follow up of each patients will be done at 3 and 6 months
Eligibility criteria
Qualifiers
Adult patients older than 16 yrs old.
Patients with traumatic median or ulnar nerve injury who are complaining of symptoms or functional disability.
Patients with these injuries for more than 3 months
Disqualifiers
1- Presence of other causes of nerve affection (entrapment, Diabetes, etc).
Trial design
Treatments tested in this trial
- perineural injection