Understanding How Movements Are Transferred From Task to Task in Parkinson's Disease
ConditionPARKINSON DISEASE (Disorder)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorMcGill University
About this trial
The purpose of this study is to understand how a specific brain area, the Posterior Parietal Cortex (PPC), plays a role in movement transfer from walking on a split-belt treadmill (SBT) to walking on the ground in people with Parkinson's disease (PwPD).
Here, investigators will apply repeated transcranial magnetic stimulation (rTMS) to upregulate the PPC. Then, the differences in the gait parameters between pre- and post-interventions will be compared between the TMS-active and the TMS-sham.
Eligibility criteria
Qualifiers
a confirmed diagnosis of idiopathic Parkinson's disease
absence of freezing of gait confirmed by a "No" answer to the second item of the New Freezing of Gait Questionnaire (NFOGQ) and no observation of FOG during a freezing provoking test
no other neurological diagnosis
no severe musculoskeletal/orthopedic or vestibular condition that interferes with walking and or significantly affects balance
Disqualifiers
severe dyskinesia that interacts with walking and balance hearing or visual impairment
observed inability to walk safely on a tied-belt treadmill
neurological disorders other than PD or other pathology (e.g., orthopedic) interfering with mobility. - contradiction for TMS
implanted deep brain stimulator.
Trial design
Treatments tested in this trial
- Transcranial Magnetic Stimulation Active
- Transcranial Magnetic Stimulation Sham
Treatment groups
24 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov