Understanding Motivation in Parkinson's Patients Through Neurophysiology

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, San Francisco

About this trial

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Eligibility criteria

Qualifiers

Has Parkinson's Disease or Dystonia

Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN

Has DBS device implanted either bilaterally or unilaterally

Male or female

Disqualifiers

Severe cognitive impairments

Has MOCA score below 20

Pregnancy

Age less than 18 years old

Trial design

Treatments tested in this trial

  • Stimulation on
  • Stimulation off
  • Decision Making Task

Treatment groups

70 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of California, San Francisco

Lead sponsor

Yale University

Collaborator

Rune Labs

Collaborator

University of Birmingham

Collaborator