About this trial
Unintentional weight loss (UWL) is commonly associated with a wide variety of diseases and there is still no valid diagnostic pathway for evaluating UWL. When detecting UWL coupled with GRAIL Galleri testing, (an investigational pan-cancer early detection test), it is thought that there is a greater positive predictive value in detecting malignancies. This study aims to test the potential synergistic effects of UWL detection and GRAIL usage to detect malignancy at an even earlier rate. UWL will be measured using weekly weight tracking.
Eligibility criteria
Qualifiers
Age range: from 40 to 80 years
Access to a device (cellphone, computer, tablet) that is compatible with the Fitbit Aria Air smart scale utilized in this study
Willing to comply with all study procedures and be available for the duration of the study
Subjects must be mentally competent and must have the ability to understand and the willingness to sign a written informed consent document
Disqualifiers
Active cancer diagnosis - current diagnosis, currently undergoing cancer treatment, or concluded cancer treatments within 3 years
Actively trying to lose weight with medications or bariatric surgery
Pregnant
Trial design
Treatments tested in this trial
- GRAIL Galleri
Treatment groups
Sponsors and collaborators
Case Comprehensive Cancer Center
Lead sponsor
University Hospitals Seidman Cancer Center
Collaborator