To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.
Female patients aged between 55-75.
Patients those who are diagnosed with organ-confined urothelial carcinoma（<pT3）
Patients those who are capable for radical cystectomy with orthotopic ileal neobladder.
ECOG score between 0-2;
Absence of tumour in bladder neck or urethra;
Patients thsoe who are diagnosed distant metastasis before surgery.
Previous history of malignancy of pelvic organs or surgical resection of pelvic organs;
Patients those who are diagnosed with other malignancies.;
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lead sponsor
Peking University Third Hospital
Collaborator