Urine Alkalinization for UTI in Women: RCT
ConditionUTI - Urinary Tract Infection
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorAssiut University
About this trial
The goal of this clinical trial is to evaluate whether urinary alkalinization using potassium citrate can relieve symptoms and improve urine culture results in women aged 18 to 50 years with uncomplicated urinary tract infections (UTIs). The main questions it aims to answer are:
Does urinary alkalinization reduce UTI symptom scores by Day 7?
Does it lead to better urine culture results compared to antibiotic?
Researchers will compare urinary alkalinization with potassium citrate to antibiotic to see if it provides more symptom relief and better microbiological outcomes.
Participants will:
Take either potassium citrate or antibiotic
Be assessed for symptoms and adverse events on Day 7
Provide a urine sample for culture before and after treatment
Report any return visits due to worsening symptoms or medication side effects
Eligibility criteria
Qualifiers
Women aged ≥ 18 and ≤ 50.
Symptoms of uncomplicated UTI or cystitis; including urinary frequency, urgency and dysuria.
Positive urine culture of mid-urine urine.
Disqualifiers
Post menopausal women.
Pregnancy.
Complicated UTIs, such as those requiring hospital admission, infections associated with fevers, those with urinary tract abnormalities, urinary tract calculi or urinary tract obstruction.
History of recurrent UTI.
Trial design
Treatments tested in this trial
- potassium citrate
- Nitrofurantoin
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov