Use of Neuromuscular Electrical Stimulation to Prevent Exercise Resistance
ConditionFat Metabolism
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorColorado State University
About this trial
The study will find out if 100 minutes of electrical stimulation of muscle prevents the unfavorable consequence of insufficient exercise.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Regularly active (more than 30 minutes of exercise per day, 3 days per week, over the previous 12 months)
Ability to complete at least one hour of treadmill exercise (i.e. jogging/running),
Willing to abstain from caffeine and alcohol for 24-hours prior to three different study visits
Competency in English
Disqualifiers
Current or previous injuries that may hinder a participant's ability to exercise on a treadmill
A history of cardiopulmonary disorder that may be contra-indicative to treadmill exercise
Current use of cardio-pulmonary medication to treat a cardio-pulmonary condition
Currently breastfeeding
Trial design
Design model
Crossover
Treatments tested in this trial
neuromuscular electrical stimulation
Other interventionThe study participants will engage in 100-minutes of neuromuscular electrical stimulation (NMES). NMES pads are sticky pieces of plastic, similar in size to a 25-cent coin. The pads will be placed on the bellies of thigh muscles (the vastus lateralis, vastus medialis), and calf muscles (the long and short head of the gastrocnemius). These skeletal muscles are selected due to their size (thereby promoting a bigger increase for metabolic rate compared with a small muscle), because they are relatively superficial, and because previous published studies of NMES used these anatomical locations.
Treatment groups
30 Participants
are divided into 3 treatment groupsGroup A: Establishing the normal benefit of exerciseNo intervention 0 interventions
Group B: Demonstrating exercise resistanceNo intervention 0 interventions
Group C: Trying to prevent exercise resistanceExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Fat oxidation
Circulating triglyceride concentration after eating a high fat meal.
Time frame
Blood will be sampled and triglyceride concentration measured. Study participants will eat a meal. Blood will be sampled and triglyceride concentration measured every 30-minutes for 4 hours.Sponsors and contacts
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Source ClinicalTrials.gov