About this trial
Following lower-limb amputation, the loss of somatosensory information from the missing limb renders walking less automatic, more cognitively demanding, and often asymmetric, which can lead to secondary pathologies.
Hypothesis: This study is based on the hypothesis that phantom limb sensations (PLS), when coherent with the prosthetic device's movements and the phases of the gait cycle, can compensate for the loss of somatosensory feedback and thereby improve locomotion for individuals with amputation. It is further hypothesized that it is possible to artificially induce these coherent and useful sensations, notably through "referred sensations" elicited by stimulation of the residual limb (e.g., via the prosthetic socket).
Objectives: The project aims to:
* Determine whether the natural presence of phantom limb sensations during walking impacts gait parameters. * Confirm in a larger patient population that modifications to the prosthetic socket can induce or enhance phantom sensations that are perceived as useful for walking. * Investigate whether these perceptual changes (induced or enhanced) are associated with objective, measurable improvements in gait quality.
Eligibility criteria
Qualifiers
Major lower limb amputation
Understand and be able to express oneself in the French language (for semi-structured interviews)
Affiliated with a social security scheme
No major surgery on the lower limbs for at least 3 years
Disqualifiers
History of psychiatric disorders
Pregnant or breastfeeding woman
Minor
Adult subject to a legal protection measure
Trial design
Treatments tested in this trial
- Gait analysis
- Mapping of referred sensations.
- Exploration of the areas of the brain activated during referred sensations
- Evaluation of the effects of socket modifications on phantom sensations and walking
- Phantom limb interview
Treatment groups
Sponsors and collaborators
Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Lead sponsor
Clinique Chantecler
Collaborator
Centre Orthopédique Maguelone
Collaborator
Centre Helio Marin
Collaborator
Institut universitaire de réadaptation Valmante Sud
Collaborator
Institut des Sciences du Mouvement
Collaborator