Using Artificial Intelligence to Guide Fluid Therapy During Major Cancer Surgery: A Randomized Controlled Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNational Cancer Institute, Naples

About this trial

The goal of this clinical trial is to learn if using artificial intelligence to guide intravenous fluid therapy during major cancer surgery can help keep blood pressure more stable compared with usual care in adult patients undergoing major cancer surgery. The main questions it aims to answer are:

* Does artificial intelligence-guided fluid therapy reduce hypotensive events during surgery? * Does this approach improve recovery and reduce complications after major cancer surgery?

Researchers will compare artificial intelligence-guided fluid therapy with standard fluid management to see if the artificial intelligence-guided approach provides better support during surgery.

Participants will:

* Undergo major cancer surgery under general anesthesia * Receive either artificial intelligence-guided fluid management or standard fluid management during surgery * Be monitored during and after surgery as part of routine clinical care * Be followed after surgery to assess recovery and possible complications

Eligibility criteria

Qualifiers

Age ≥ 18 years

American Society of Anesthesiologists (ASA) Physical Status II-IV

Undergoing major abdominal oncologic surgery (open or laparoscopic) with an expected duration >2 hours

Planned invasive arterial pressure monitoring

Disqualifiers

Significant arrhythmias (e.g., persistent atrial fibrillation)

Severe aortic stenosis

Emergency surgery

Sepsis

Trial design

Treatments tested in this trial

  • Artificial Intelligence-Assisted Fluid Management
  • Standard fluid management

Treatment groups

176 Participants
are divided into 2 treatment groups