The goal of this study is to better understand how blood flows and how oxygen is utilized in the lower limbs of people who suffer from peripheral artery disease. This study will also assess how these factors affect treatment outcomes.
Specific aims include:
Aim 1: Utilize BB-NIR-DCS to differentiate PAD patients experiencing primary oxygen delivery limitations from those suffering from mitochondrial dysfunction.
Aim 2: Test the efficacy of BB-NIR-DCS at predicting individual responses to vascular intervention.
Cases, Aim 1
18 or older
willing to participate under the conditions described in the informed consent form (ICF)
eligible to sign the ICF
Cases, Aim 1
Ankle-Brachial Index >0.9 or <0.4
isolated disease in aorta/iliac vessels
unstable angina or myocardial infarction in past 12 months