About this trial
Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder. While effective and early interventions can mitigate the impact of late talking, not enough is known about its neural basis, yet is needed to inform the design of more individualized interventions. This proposed effort uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie learning and late talking, while also considering their association to treatment-related changes in LT.
Eligibility criteria
Qualifiers
child and parent are monolingual/native (primarily) English speakers
child is enrolled at one of the participating facilities
child is recruited via word of mouth, including social media
child is between 18 and 30 months of age
Disqualifiers
Child does not meet criteria for LT or typical development
Standard magnetic resonance imaging exclusion criteria
Gestational age less than 37 weeks or greater than 42 weeks
Special education placement of child based on ability or behavior
Trial design
Treatments tested in this trial
- Intervention to address late talking
Treatment groups
Sponsors and collaborators
University of Toronto
Lead sponsor
Holland Bloorview Kids Rehabilitation Hospital
Collaborator
Children's Hospital Medical Center, Cincinnati
Collaborator
University of Cincinnati
Collaborator
Georgetown University
Collaborator