Using Neuroimaging and Behavioral Assessments to Understand Late Talking

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorUniversity of Toronto

About this trial

Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder. While effective and early interventions can mitigate the impact of late talking, not enough is known about its neural basis, yet is needed to inform the design of more individualized interventions. This proposed effort uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie learning and late talking, while also considering their association to treatment-related changes in LT.

Eligibility criteria

Qualifiers

child and parent are monolingual/native (primarily) English speakers

child is enrolled at one of the participating facilities

child is recruited via word of mouth, including social media

child is between 18 and 30 months of age

Disqualifiers

Child does not meet criteria for LT or typical development

Standard magnetic resonance imaging exclusion criteria

Gestational age less than 37 weeks or greater than 42 weeks

Special education placement of child based on ability or behavior

Trial design

Treatments tested in this trial

  • Intervention to address late talking

Treatment groups

45 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Toronto

Lead sponsor

Holland Bloorview Kids Rehabilitation Hospital

Collaborator

Children's Hospital Medical Center, Cincinnati

Collaborator

University of Cincinnati

Collaborator

Georgetown University

Collaborator