Using Personalized Assessments in the Treatment of Childhood OCD
ConditionObsessive-Compulsive Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age8-17
SponsorJohns Hopkins University
About this trial
The primary purpose of this study is to learn whether personalized assessment of obsessive-compulsive disorder (OCD) symptoms in childhood OCD using mobile health technology are feasible and acceptable for youth and parents. The investigators will also examine whether personalized cognitive-behavioral therapy (CBT) that is informed by personalized OCD assessments yields better clinical outcomes when compared to standard CBT for youth with OCD
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
be 8-17 years of age;
meet diagnostic criteria for a primary diagnosis of OCD on a structured clinical interview;
have moderate OCD severity as evidenced by a CY-BOCS total score of ≥16;
medication free and/or on a stable dose of medication 8 weeks prior to study participation;
Disqualifiers
the presence of psychotic disorder, bipolar disorder, or autism spectrum disorders;
significant suicidal ideation that warrants medical intervention;
concurrent psychotherapy for OCD;
inability to complete scales, or attend visits.
Trial design
Design model
Parallel
Treatments tested in this trial
Personalized Assessments
Other interventionPersonalized CBT will use individualized OCD symptom networks to guide CBT strategies to target central symptom nodes in contemporaneous networks.
Standard of Care
Other interventionThe standard CBT condition will use standard-of-care approaches to guide CBT strategies to target OCD symptoms.
Treatment groups
30 Participants
are divided into 2 treatment groupsGroup A: Personalized AssessmentsExperimental treatment 1 intervention
Group B: Standard of CareActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Children's Yale-Brown Obsessive-Compulsive Scale Second Edition (CY-BOCS-II) Total Severity Score
A clinician-rated measure of OCD symptom severity in the past week. This 10-item measure is rated on a 0 to 5 scale with a total score ranging from 0 to 50. A higher total score is reflective of greater OCD symptom severity.
Time frame
Screen, Baseline (Week 0), Week 4, Week 8, and Week 12Sponsors and contacts
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Source ClinicalTrials.gov