Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorH. Lee Moffitt Cancer Center and Research Institute

About this trial

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.

Eligibility criteria

Qualifiers

Individuals who present to the GI clinic, surgery, or endoscopy at Moffitt, Florida Research Institute (FRI), or UM with a clinical suspicion for (or diagnosis of) a pancreatic lesion, cyst, mass, cancer, or pancreatitis based on symptoms, imaging, or blood-work and has not had any treatment involving their pancreas.

Able to understand and voluntarily sign the informed consent.

Willing to complete study questionnaire(s) and donate medical images and/or biological specimens (including blood, cystic fluid, and/or tissue) obtained at the time of standard of care procedures (biopsy, surgery, and venipuncture) after signing the informed consent document

Disqualifiers

No suspicion or diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis.

Has a diagnosis of a pancreatic lesion, cyst, mass, cancer, or pancreatitis and has already undergone treatment involving the pancreas (which may involve surgery, chemo- or immuno-therapy, and/or radiation).

Unable to provide informed consent.

Unwilling to complete study questionnaire(s) and/or donate biological specimens or images.

Trial design

Treatments tested in this trial

  • Blood Sample collection
  • Tissue sample collection
  • Data collection

Treatment groups

1,174 Participants
are divided into 2 treatment groups

Sponsors and collaborators

H. Lee Moffitt Cancer Center and Research Institute

Lead sponsor

National Cancer Institute (NCI)

Collaborator

University of Florida

Collaborator

University of Miami

Collaborator